Formulation: A solid
Formal Name: (SA-8-1425362′5′)-[rel-10-[(2R,3S)-2-(hydroxy-κO)-3-hydroxy-1-(hydroxymethyl)propyl]-1,4,7,10-tetraazacyclododecane-1,4,7-triacetato(3-)-κN1,κN4,κN7,κN10,κO1,κO4,κO7]-gadolinium
Purity: ≥95%
Formula Markup: C18H31GdN4O9
Formula Weight: 604,7
Shelf life (days): 1460
CAS Number: 770691-21-9
Notes: Gadobutrol is a gadolinium-based MRI contrast agent.{72218} It enhances the visibility of hepatic tumors in a rat model of hepatocellular carcinoma (HCC) induced by N-nitrosomorpholine when administered at a dose of 0.1 mmol/kg. Gadobutrol (0.1 mmol/kg per day for three weeks) increases memory deficits in the passive avoidance test and decreases immobility time in an open field test in rats.{72219} Formulations containing gadobutrol have been used as contrast agents for diagnostic MRI in adults and children.
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