Clone Name: 35DAG/21B5
Light Chain: Kappa
Application Note: IHC-Fr: 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 32
Form: Liquid
Buffer (with preservative): Tissue culture supernatant, 0.09% Sodium azide.
Concentration:
Background: This gene encodes gamma-sarcoglycan, one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. The dystrophin-glycoprotein complex (DGC) spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Defects in the encoded protein can lead to early onset autosomal recessive muscular dystrophy, in particular limb-girdle muscular dystrophy, type 2C (LGMD2C). [provided by RefSeq, Oct 2008]
Uniprot ID: Q13326
Antigen Species: Rabbit
Immunogen: Synthetic peptide containing amino acids 167–178 of the rabbit gamma-sarcoglycan sequence (Noguchi et al., 1995).
Purification: Unpurified
Conjugation: Unconjugated
Full Name: sarcoglycan gamma
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