Gantenerumab Biosimilar - Research Grade

Gantenerumab Biosimilar - Research Grade, Human IgG1

Target: Amyloid Beta.

Specificity: Detects human amyloid β. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Gantenerumab.

Purification method: This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Background: RUO gantenerumab is a monoclonal antibody for the treatment of Alzheimer’s disease being developed by Hoffmann-La Roche pharmaceuticals. Gantenerumab binds to and clears aggregated beta amyloid fibers. A phase III clinical trial of gantenerumab was stopped early because of a lack efficacy.

Concentration: 5mg/ml.

Formulation: Sterile, preservative-free, solution in PBS. BSA and Azide free.

Purity: >95% by SDS-PAGE.

Endotoxin: ≤ 1.0 EU/mg as determined by the LAL method.

Use: Products are for research use only. Not for use in diagnostic or therapeutic procedures.

• SKU: ICH5009-20MG
• Manufacturer: Ichorbio
• Manufacturer SKU: ICH5009-20MG
• Package Unit: 20mg
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Functional Assay
• Isotype: Human IgG1