Conjugation: HRP: Horseradish Peroxidase
Description of Target: GCET2 is a protein which may function in signal transduction pathways and whose expression is elevated in germinal cell lymphomas. It contains a putative PDZ-interacting domain, an immunoreceptor tyrosine-based activation motif (ITAM), and two putative SH2 binding sites. In B cells, its expression is specifically induced by interleukin-4.This gene encodes a protein which may function in signal transduction pathways and whose expression is elevated in germinal cell lymphomas. It contains a putative PDZ-interacting domain, an immunoreceptor tyrosine-based activation motif (ITAM), and two putative SH2 binding sites. In B cells, its expression is specifically induced by interleukin-4. Alternative splicing results in multiple transcript variants encoding different isoforms.
Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GCET2
Key Reference: Lu,X., (2007) Blood 110 (13), 4268-4277
Molecular Weight: 21kDa
Peptide Sequence: Synthetic peptide located within the following region:
YSLLHMPSTDPRHARSPEDEYELLMPHRISSHFLQQPRPLMAPSETQFSHProduct Format: Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Protein Name: Germinal center-associated signaling and motility protein
Protein Size: 178
Purification: Affinity Purified
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