GDF-11

Product Description: Growth Differentiation Factor 11 (GDF-11), also known as BMP-11, is a regulator of cell growth and differentiation during muscular and neural development. GDF-11 binds the Transforming Growth Factor β receptors ALK4, ALK5, and ALK7 to activate SMAD signaling. In adults, exogenous GDF-11 promotes cardiomyocyte regeneration to reverse age-related cardiac hypertrophy.

Growth Factor AA Sequence: NLGLDCDEHS SESRCCRYPL TVDFEAFGWD WIIAPKRYKA NYCSGQCEYM FMQKYPHTHL VQQANPRGSA GPCCTPTKMS PINMLYFNDK QQIIYGKIPG MVVDRCGCS

• SKU: CGSGFH57-20
• Manufacturer: Cell Guidance Systems
• Manufacturer SKU: GFH57-20
• Package Unit: 20 μg
• Quantity Unit: STK
• Reactivity: Human