Product Type: Inhibitor
CAS No.: 184475-35-2
MolecularFormula: C22H24ClFN4O3
Molecular Weight: 446,9
Source: Synthetic
Purity: >99%
Solubility: Soluble in DMSO (89 mg/ml at 25 °C), methanol (20 mg/ml), ethanol (4 mg/ml at 25 °C), DMF (20 mg/ml), and water (<1 mg/ml at 25 °C)
Appearance: Solid
PubChem CID: 123631
Scientific Background: Gefitinib is a selective inhibitor of EGFR tyrosine kinase by blocking EGFR autophosphorylation.
References: 1. Ciardiello F., et al. (2000) Clin. Cancer Res. 6(5): 2053–2063.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.