Gemtuzumab ozogamicin (solution), CAS 220578-59-6

Gemtuzumab ozogamicin (solution), CAS 220578-59-6
SKU
MEXHY-109539A-0
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MedChemExpress

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Product Description: Gemtuzumab ozogamicin (solution) is an antibody-drug conjugate (ADC) consisting of a humanized immunoglobulin (IgG4) antibody directed against CD33 that is conjugated to the cytotoxic agent Calicheamicin (HY-19609). Calicheamicin is a cytotoxic antibiotic. Gemtuzumab ozogamicin can be used for the research of acute myeloid leukemia (AML)[1][2].

Applications: Cancer-programmed cell death

Formula: N/A

References: [1]Yi Liu, et al. CD33-directed immunotherapy with third-generation chimeric antigen receptor T cells and gemtuzumab ozogamicin in intact and CD33-edited acute myeloid leukemia and hematopoietic stem and progenitor cells. Int J Cancer. 2022 Apr 1;150(7):1141-1155./[2]Baron J, et al. Gemtuzumab ozogamicin for the treatment of acute myeloid leukemia. Expert Rev Clin Pharmacol. 2018;11(6):549-559.

CAS Number: 220578-59-6

Molecular Weight: 151000 (average)

Research Area: Cancer

Target: Antibody-Drug Conjugates (ADCs);Apoptosis
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SKU MEXHY-109539A-0
Manufacturer MedChemExpress
Manufacturer SKU HY-109539A-0
Package Unit Get quote
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