Application Note: WB: 1:500-1:2000. IHC-P: 1:50-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 170
Form: Liquid
Buffer (with preservative): PBS, 50% Glycerol, 0.01% thiomersal.
Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a protein which belongs to the C2H2-type zinc finger proteins subclass of the Gli family. They are characterized as DNA-binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling. The protein encoded by this gene localizes in the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. Mutations in this gene have been associated with several diseases, including Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, and postaxial polydactyly types A1 and B. [provided by RefSeq, Jul 2008]
Uniprot ID: P10071
Antigen Species: Human
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 800-900 of human GLI3 (NP_000159.3).
Purification: Purified by affinity chromatography
Conjugation: Unconjugated
Full Name: GLI family zinc finger 3
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