Immunogen: Peptide with sequence C-HFLPWIRSHTKEEN from the C-terminal of the Urokinase sequence.
Concentration: 0.5mg/ml
Format: Purified
Storage buffer: TRIS buffered saline0.02%Sodium Azide (NaN3)0.5%Bovine Serum Albumin
Additional info: Goat anti Human Urokinase antibody detects an epitope within the C-terminal of urokinase, a potent ~50 kDa serine protease also known as urokinase plasminogen activator (uPA). uPA cleaves and activates plasminogen to form plasmin and is involved in extracellular cellular matrix degradation and cell signalling. uPA and its receptor are involved in the pathogenesis of inflammation and immunity.A specific polymorphism in the gene encoding uPA may be associated with late-onset Alzheimer's disease (Ertekin-Taner et al. 2005). The levels of uPA, uPAR and its soluble fragments have also been found to be increased in tissues, plasma and other body fluids of cancer patients and to be markers of cancer development and metastasis (Kim et al. 2016). Storage: This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
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