gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/2038), 1mg/mL

gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/2038), 1mg/mL
SKU
BTMBNUM2038-50
Packaging Unit
50 uL
Manufacturer
Biotium

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Description: Cytotoxic T lymphocytes (CTLs) recognize melanoma-associated antigens, which belong to three main groups. These groups include tumor-associated testis-specific antigens, melanocyte differentiation antigens and mutated or aberrantly expressed antigens, which are routinely used as markers to identify melanomas based on their binding to specific monoclonal antibodies. gp100, also designated ME20-M, ME20-S and PMEL 17, is classified as a melanocyte differentiation antigen and is expressed at low levels in normal cell lines and tissues, but is upregulated in melanocytes. gp100 is a highly glycosylated protein. It is also the product of proteolytic cleavage, which results in a secreted protein.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Conjugate: Purified, BSA-free

Concentration: 1 mg/mL

Storage buffer: PBS, no BSA, no azide

Product Origin: Animal - Mus musculus (mouse)

Clone: PMEL/2038

Entrez Gene ID: 6490

Immunogen: Recombinant human SILV protein fragment (around aa 376-502) (exact sequence is proprietary)

Verified AB Applications: IHC (FFPE) (verified)/WB (verified)

Z-Antibody Applications: IHC, FFPE (verified)/WB (verified)
More Information
SKU BTMBNUM2038-50
Manufacturer Biotium
Manufacturer SKU BNUM2038-50
Package Unit 50 uL
Quantity Unit STK
Reactivity Human
Clonality Monoclonal
Application Western Blotting, Immunohistochemistry
Isotype IgG1 kappa
Host Mouse
Conjugate Unconjugated
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