Clone Name: 11F1
Application Note: IHC-P: 1:80. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 28
Form: Liquid
Buffer (with preservative): Tissue culture supernatant, 0.09% Sodium azide.
Concentration:
Background: This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis. [provided by RefSeq, Sep 2016]
Uniprot ID: P10144
Antigen Species: Human
Immunogen: Recombinant prokaryotic fusion protein corresponding to the N-terminus of the mature granzyme B molecule.
Purification: Unpurified
Conjugation: Unconjugated
Full Name: granzyme B
English
Deutsch
