Application Note: WB: 1:2000. IHC-P: 1:50-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 21
Form: Liquid
Buffer (with preservative): PBS, 0.09% sodium azide.
Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)
Background: Enables receptor ligand activity; transmembrane receptor protein tyrosine kinase activator activity; and vascular endothelial growth factor receptor 2 binding activity. Involved in several processes, including cell migration involved in sprouting angiogenesis; nephron epithelium morphogenesis; and positive regulation of macromolecule metabolic process. Acts upstream of or within several processes, including positive regulation of NF-kappaB transcription factor activity; positive regulation of branching involved in ureteric bud morphogenesis; and regulation of signal transduction. Located in extracellular space. Colocalizes with cell surface. Is expressed in several structures, including embryo mesenchyme; limb bud; neural ectoderm; sensory organ; and skeleton. Orthologous to human GREM1 (gremlin 1, DAN family BMP antagonist). [provided by Alliance of Genome Resources, Apr 2022]
Uniprot ID: O70326
Antigen Species: Mouse
Immunogen: KLH conjugated synthetic peptide between 147-175 amino acids from the C-terminal region of mouse GREMLIN.
Purification: Protein A purified followed by antigen-affinity chromatography
Conjugation: Unconjugated
Full Name: gremlin 1, DAN family BMP antagonist
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