Scientific Background: GSK690693 Hydrochloride is an ATP-competitive pan-Akt kinase inhibitor. It is derived from aminofurazan. It has shown to produce antiproliferative and apoptotic effects in tumor cell lines.
References: 1. Heerding D.A., et al. (2008) J. Med. Chem. 51(18): 5663–5679. 2. Rhodes N., et al. (2008) Cancer Res. 68(7): 2366–2374.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.