Conjugation: FITC: Fluorescein Isothiocyanate
Description of Target: GTF2B is the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II.This gene encodes the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GTF2B
Key Reference: Elsby,L.M., (2006) EMBO Rep. 7 (9), 898-903
Molecular Weight: 35kDa
Peptide Sequence: Synthetic peptide located within the following region:
SVAAAAIYMASQASAEKRTQKEIGDIAGVADVTIRQSYRLIYPRAPDLFPProduct Format: Liquid. Purified antibody supplied in 1x PBS buffer.
Protein Name: Transcription initiation factor IIB
Protein Size: 316
Purification: Affinity Purified