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Clone Name: HL2170
Light Chain: Kappa
Application Note: WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 32
Form: Liquid
Buffer (with preservative): PBS, no preservative.
Concentration: 2 mg/ml (Please refer to the vial label for the specific concentration.)
Background: The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot ID: O00165
Antigen Species: Human
Immunogen: Recombinant fragmemt of human HAX1
Purification: Affinity purified by Protein A.
Conjugation: Unconjugated
Full Name: HCLS1 associated protein X-1
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