Products from BPS Bioscience require a minimum order value above 400€Encompassing Amino Acids: full length
Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Assay Conditions: 25 mM Tris/HCl, pH 8.0, 137 mM NaCl, 2.7 mM KCl, 1 mM MgCl
2, 0.05% Triton X-100, 0.1 mg/ml BSA, 20 µM BPS HDAC substrate 1 (Catalog #50040), and HDAC11 (0.4 - 25 ng). Incubation condition: 30 min at 37°C followed by developing for 15 min at room temperature.
Description: Human HDAC11 (full length) (GenBank Accession No. NM_024827) untagged, MW= 39.6 kDa, expressed in baculovirus expression system.
Format: Aqueous buffer solution
Formulation: 50 mM Tris-HCl, pH 8.0, 500 mM NaCl, 50 mM KCl, 2 mM EDTA, 3 mM DTT, 0.5% Triton-X-100 and 10% Glycerol.
Genbank: NM_024827
Host Cell Line: Sf9 cells
Storage Stability: At least 6 months at -80°C.
Tags: none
Uniprot: Q96DB2
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002). Application Reference:
Design, synthesis, 3D pharmacophore, QSAR, and docking studies of carboxylic acid derivatives as Histone Deacetylase inhibitors and cytotoxic agents (2014)
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