Formulation: A neat oil
Formal Name: 2,2,3,3,4,4,4-heptafluoro-butanoic acid
Purity: ≥80%
Formula Markup: C4HF7O2
Formula Weight: 214
Shelf life (days): 1460
CAS Number: 375-22-4
Notes: Heptafluorobutyric acid is a perfluoroalkyl substance (PFAS).{67175} Chronic topical administration of heptafluorobutyric acid (25 µl of a 3.75-15% v/v solution) on the ear increases liver and kidney weight in mice. It induces multifocal hepatocyte necrosis and centrilobular hepatocyte hypertrophy when administered topically at a concentration of 7.5% v/v. Heptafluorobutyric acid (15% v/v) increases serum cholesterol and alkaline phosphatase (ALP) levels and decreases serum urea nitrogen levels. It has been found in marine life and as a contaminant in surface water.{66209,67174} Formulations containing heptafluorobutyric acid have been used as ion pair reagents for reverse-phase HPLC and in the synthesis and solubilization of proteins and peptides.
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