Products from BPS Bioscience require a minimum order value above 400€Encompassing Amino Acids: 2-58
Applications: Useful as a substrate for methyltransferases or acetyltransferases and for screening small molecular inhibitors of histone methyltransferases for drug discovery.
Description: Human Histone 3 (GenBank Accession No. NM_003532), a.a. 2-58 with N-terminal GST-tag, MW = 32 kDa, expressed in an E. coli expression system.
Format: Aqueous buffer solution
Formulation: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 20% glycerol, and 3 mM DTT.
Genbank: NM_003532
Host Cell Line: E. coli
Storage Stability: At least 6 months at -80°C.
Tags: N-terminal GST-tag
Uniprot: P68431
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: 1. Loyola, A. et al., Mol. Cell 24 (2), 309-316 (2006).
2. Groth, A. et al., Mol. Cell 17 (2), 301-311 (2005).Application Reference(s):
Differential mode of antimicrobial actions of arginine-rich and lysine-rich histones against Gram-positive Staphylococcus aureus (2013)
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