Conjugation: Biotin
Description of Target: In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. HOXA11 gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is involved in the regulation of uterine development and is required for female fertility. Mutations in this gene can cause radio-ulnar synostosis with amegakaryocytic thrombocytopenia.In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is involved in the regulation of uterine development and is required for female fertility. Mutations in this gene can cause radio-ulnar synostosis with amegakaryocytic thrombocytopenia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HOXA11
Key Reference: Connell,K.A., (2008) J. Clin. Invest. 118 (3), 1050-1055
Molecular Weight: 34kDa
Peptide Sequence: Synthetic peptide located within the following region:
FETAYGTPENLASSDYPGDKSAEKGPPAATATSAAAAAAATGAPATSSSDProduct Format: Liquid. Purified antibody supplied in 1x PBS buffer.
Protein Name: Homeobox protein Hox-A11
Protein Size: 313
Purification: Affinity Purified
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