Products from BPS Bioscience require a minimum order value above 400€
Applications: Great for screening small molecular inhibitors for drug discovery and HTS applications.
Description: The HSP90β (C-Terminal) TR-FRET assay kit is designed to measure the inhibition of HSP90αbinding to its protein target PPID (also known as Cyclophilin D or Cyp40) in a homogeneous,384 reaction format. This assay requires no time-consuming washing steps, making it especiallysuitable for high throughput screening applications. The assay procedure is straightforward andsimple. A sample containing terbium-labeled donor, dye-labeled acceptor, HSP90β, substrate,and an inhibitor is incubated for 2 hours. The protein-protein interaction is then assayed bymeasuring the TR-FRET between the PPID and HSP90β using a fluorescence reader.
Storage Stability: Stable at least 6 months from date of receipt, when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival.
Supplied As: Comes in a homogeneous, 384 reaction format
Uniprot: P08238
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: Allan, R.K. et al. J. Biol. Chem. 2006 281(11): 7161-71
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