Conjugation: HRP: Horseradish Peroxidase
Description of Target: In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage.
Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HSPA6
Key Reference: Noonan,E.J., (2007) Cell Stress Chaperones 12 (4), 393-402
Molecular Weight: 71kDa
Peptide Sequence: Synthetic peptide located within the following region:
EYEHQKRELEQICRPIFSRLYGGPGVPGGSSCGTQARQGDPSTGPIIEEVProduct Format: Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Protein Name: Heat shock 70 kDa protein 6
Protein Size: 643
Purification: Affinity Purified
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