Abbreviation: HTR2B
Target Synonym: HTR2B;5-HT(2B);5-HT-2B;5-HT2B
Conjugation: Unconjugated
UNIProt ID: P41595
Background: This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved. Alternatively spliced transcript variants have been found for this gene.
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human HTR2B
Dilution: WB 1:200-1:1000
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