Species: Human
Application Note: The reaction rate of GTX02798-pro Human Autotaxin (mature) protein (at different concentrations) were measured in FS-3 assay.
Form: Liquid
Buffer (with preservative): PBS, 20% Glycerol, no preservative.
Concentration: batch dependent (Please refer to the vial label for the specific concentration.)
Background: The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2008]
Uniprot ID: Q13822
Region Sequence: C-terminal 10 x His tagged ; 49-863 aa (Uniprot #Q13822)
ExpressionSystem: HEK293 cells
Conjugation: Unconjugated
Full Name: ectonucleotide pyrophosphatase/phosphodiesterase 2
English
Deutsch
