Product Description: Human IgG1 kappa, Isotype Control conjugated with MMAE is a human monoclonal antibody that is an isotype control of human IgG1κ antibody and has an inhibitory effect on tubulin polymerization. Human IgG1 kappa, Isotype Control conjugated with MMAE can be used to synthesize antibody conjugate molecules (ADCs)[1].
Applications: Cancer-programmed cell death
Formula: N/A
References: [1]Kuo W Y, et al. Antibody-drug conjugates with HER2-targeting antibodies from synthetic antibody libraries are highly potent against HER2-positive human gastric tumor in xenograft models[C]//MAbs. Taylor & Francis, 2019, 11(1): 153-165.
Molecular Weight: N/A
Research Area: Cancer
Target: Antibody-Drug Conjugates (ADCs)