Human IgM (Immunoglobulin Mu Heavy Chain) (B-Cell Marker)(rIGHM/3802), CF740 conjugate, 0.1mg/mL

Human IgM (Immunoglobulin Mu Heavy Chain) (B-Cell Marker)(rIGHM/3802), CF740 conjugate, 0.1mg/mL
SKU
BTMBNC743802-100
Packaging Unit
100 uL
Manufacturer
Biotium

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Description: Recognizes a protein of 75 kDa, identified as mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. IgM antibody is prominent in early immune responses to most antigens. Aberrant levels are associated with immune deficiency states, hereditary deficiencies, myeloma, Waldenstrom's macroglobulinemia, chronic infection and hepatocellular disease. This MAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Conjugate: CF740

Concentration: 0.1 mg/mL

Storage buffer: PBS, 0.1% rBSA, 0.05% azide

Product Origin: Animal

Clone: rIGHM/3802

Immunogen: Recombinant human full-length IGHM protein

Antibody Reactivity: IgM Mu Heavy Chain

Entrez Gene ID: 3507

Z-Antibody Applications: IHC, FFPE (verified)

Verified AB Applications: IHC (FFPE) (verified)
More Information
SKU BTMBNC743802-100
Manufacturer Biotium
Manufacturer SKU BNC743802-100
Package Unit 100 uL
Quantity Unit STK
Reactivity Human
Clonality Recombinant
Application Immunohistochemistry
Isotype IgG1 kappa
Host Mouse
Conjugate Conjugated, CF740
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