Species: Human
Application Note: Recommended antibody pairs for sandwich ELISA:Capture : GTX636571 / GTX636573, Detection : GTX636473 / GTX638598.
Calculated MW: 24
Form: Liquid
Buffer (with preservative): PBS, no preservative.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Uniprot ID: P05231
Region Sequence: C-terminal His tagged Human IL-6 protein of NP_000591.1.
ExpressionSystem: HEK293 cells
Conjugation: Unconjugated
Full Name: interleukin 6
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