Species: Human
Form: Lyophilized powder
Buffer (with preservative): Reconstitute to a concentration less than 0.1 mg/ml. Lyophilized from a 0.2 μm filtered PBS (pH 7.4), no preservatives.
Concentration:
Background: This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008]
Uniprot ID: P01116
Region Sequence: N-terminal His tagged full length human KRAS protein (Thr2-Cys185, with natural variant Gly12Val), Uniprot #P01116-2)
ExpressionSystem: E. coli
Conjugation: Unconjugated
Full Name: KRAS proto-oncogene, GTPase
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