Species: Human
Calculated MW: 53
Form: Liquid
Buffer (with preservative): PBS, 10% Glycerol, no preservative.
Concentration: 0.25 mg/ml (Please refer to the vial label for the specific concentration.)
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Background: The protein encoded by this gene is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP). [provided by RefSeq, Apr 2012]
Uniprot ID: P18428
Region Sequence: His-Tagged; 26-481aa (P18428, NP_004130.2), signal peptide removed
ExpressionSystem: HEK293 cells
Conjugation: Unconjugated
Full Name: lipopolysaccharide binding protein
English
Deutsch
