Species: Human
Calculated MW: 24,4
Form: Lyophilized powder
Buffer (with preservative): Reconstitute in 10mM PBS pH7.4 to a concentration of 0.1-1.0 mg/mL. Do not vortex. Lyophilized fromPBS pH7.4, 0.01% SKL, 5% Trehalose, no preservatives.
Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a protein that belongs to the lipocalin family. Members of this family transport small hydrophobic molecules such as lipids, steroid hormones and retinoids. The protein encoded by this gene is a neutrophil gelatinase-associated lipocalin and plays a role in innate immunity by limiting bacterial growth as a result of sequestering iron-containing siderophores. The presence of this protein in blood and urine is an early biomarker of acute kidney injury. This protein is thought to be be involved in multiple cellular processes, including maintenance of skin homeostasis, and suppression of invasiveness and metastasis. Mice lacking this gene are more susceptible to bacterial infection than wild type mice. [provided by RefSeq, Sep 2015]
Uniprot ID: P80188
Region Sequence: N-terminal His tagged full length human Lipocalin-2 protein (Gln21~Gly198: a signal peptide removed), Uniprot #P80188-1).
ExpressionSystem: E. coli
Conjugation: Unconjugated
Full Name: lipocalin 2
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