Species: Human
Product Description: M-CSF (also known as CSF1) is a cytokine that functions in the survival, proliferation, and differentiation of hematopoietic precursor cells. This bioactive recombinant human M-CSF is the 34 kDa form consisting of a disulfide-linked homodimer of two 159 a.a. subunits. Human M-CSF is active in murine systems, though the reverse is not the case.
Application Note: The ED₅₀ was determined by a cell proliferation assay using murine M-NSF-60 cells cells is ≤ 1 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁶ units/mg.
Form: Lyophilized powder
Buffer (with preservative): Reconstitute with distilled water to 0.1 mg/ml. Lyophilized from 50mM PBS, 100mM NaCl, 5% Trehalose, no Preservative.
Concentration:
Region Sequence: Human full-length M-CSF protein (33-181 a.a. of NP_000748.4, signal peptide removed)
ExpressionSystem: E. Coli
Conjugation: Unconjugated
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