HZ-1157, CAS 1009734-33-1

Formulation: A crystalline solid

Formal Name: 5-(1,1-dimethylethoxy)-2,4-quinazolinediamine

Purity: ≥98%

Formula Markup: C12H16N4O

Formula Weight: 232,3

Shelf life (days): 1460

CAS Number: 1009734-33-1

Notes: HZ-1157 is an inhibitor of hepatitis C virus (HCV) nonstructural protein 3/4A (NS3/4A) protease (IC50 = 1 µM in an NS3/4A secreted embryonic alkaline phosphatase assay).{37188} It inhibits infectious HCV virus replication in Huh7.51 cells (IC50 = 0.82 µM). It also inhibits dengue virus serotype 2 replicon activity (EC50 = 2.8 nM in BHK-D2RepT cells with high NS3 levels) without exhibiting cytotoxicity (CC50 = >10 µM).{37187}

• SKU: CAY23436-25
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 23436-25
• Green Labware: No
• Package Unit: 25 mg
• Quantity Unit: STK
• Application: Reinstoffe