Conjugation: Biotin
Description of Target: IDI1 is a peroxisomally-localized enzyme that catalyzes the interconversion of isopentenyl diphosphate (IPP) to its highly electrophilic isomer, dimethylallyl diphosphate (DMAPP), which are the substrates for the successive reaction that results in the synthesis of farnesyl diphosphate and, ultimately, cholesterol. It has been shown in peroxisomal deficiency diseases such as Zellweger syndrome and neonatal adrenoleukodystrophy that there is reduction in IPP isomerase activity.IDI1 encodes a peroxisomally-localized enzyme that catalyzes the interconversion of isopentenyl diphosphate (IPP) to its highly electrophilic isomer, dimethylallyl diphosphate (DMAPP), which are the substrates for the successive reaction that results in the synthesis of farnesyl diphosphate and, ultimately, cholesterol. It has been shown in peroxisomal deficiency diseases such as Zellweger syndrome and neonatal adrenoleukodystrophy that there is reduction in IPP isomerase activity. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-492 BE891119.1 50-541 493-1758 BX648472.1 1201-2466 1759-2150 BX537663.1 4550-4941
Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human IDI1
Key Reference: Ma,J., (2007) Atherosclerosis 191 (1), 63-72
Molecular Weight: 32kDa
Peptide Sequence: Synthetic peptide located within the following region:
PLSNPAELEESDALGVRRAAQRRLKAELGIPLEEVPPEEINYLTRIHYKAProduct Format: Liquid. Purified antibody supplied in 1x PBS buffer.
Protein Name: Isopentenyl-diphosphate Delta-isomerase 1
Protein Size: 284
Purification: Affinity Purified
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