IGF-I R, Human (His)

Product Description: IGF-I receptor (IGF1R) mediates insulin-like growth factor effects, binding strongly to IGF1. Activation triggers PI3K-AKT/PKB and Ras-MAPK pathways, influencing cell survival, protein synthesis, and proliferation. IGF1R also signals through JAK/STAT, inhibiting JNK activation. Hybrid receptors show variable binding to IGF1 and insulin. IGF-I R Protein, Human (His) is the recombinant human-derived IGF-I R protein, expressed by E. coli , with N-6*His labeled tag. The total length of IGF-I R Protein, Human (His) is 169 a.a., with molecular weight of ~27 kDa.

Formula: 3480(Gene_ID)P08069 (Y763-E931)(Accession)

Molecular Weight: Approximately 27 kDa

Compound Purity: 98.0

• SKU: MEXHY-P72256-100UG
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P72256-100UG
• Green Labware: No
• Package Unit: 100 μg
• Quantity Unit: STK