IGF1R beta antibody

Application Note: WB: 1:1000. IHC-P: 1:50-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 155

Form: Liquid

Buffer (with preservative): PBS, 0.09% Sodium azide.

Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)

Background: This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]

Uniprot ID: P08069

Antigen Species: Human

Immunogen: This IGF1 Receptor (IGF1R) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1335-1366 amino acids from the C-terminal region of human IGF1 Receptor (IGF1R).

Purification: Purified by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Conjugation: Unconjugated

Full Name: insulin like growth factor 1 receptor

• SKU: GTX25497-400
• Manufacturer: GeneTex
• Manufacturer SKU: GTX25497-400
• Green Labware: No
• Package Unit: 400 μl
• Quantity Unit: STK
• Reactivity: Human, Mouse (Murine), Rat (Rattus)
• Clonality: Polyclonal
• Application: Immunohistochemistry (paraffin), Western Blotting
• Isotype: IgG
• Human Gene ID: 3480
• Host: Rabbit