IGF1R beta antibody (HL1957)

Clone Name: HL1957

Light Chain: Kappa

Application Note: ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 155

Specificity/Sensitivity: This antibody was raised against human IGF1R Extracellular domain.

Form: Liquid

Buffer (with preservative): PBS, no preservative.

Concentration: 2 mg/ml (Please refer to the vial label for the specific concentration.)

Background: This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]

Uniprot ID: P08069

Antigen Species: Human

Immunogen: Recombinant protein encompassing a sequence within the Extracellular domain of human IGF1R. The exact sequence is proprietary.

Purification: Affinity purified by Protein A.

Conjugation: Unconjugated

Full Name: insulin like growth factor 1 receptor

• SKU: GTX637794-S-25
• Manufacturer: GeneTex
• Manufacturer SKU: GTX637794-S-25
• Green Labware: No
• Package Unit: 25 μl
• Quantity Unit: STK
• Reactivity: Human, Mouse (Murine), Rat (Rattus)
• Clonality: Monoclonal
• Application: Immunofluorescence, Immunohistochemistry (paraffin), Western Blotting, Immunocytochemistry
• Isotype: IgG
• Human Gene ID: 3480
• Host: Rabbit