Products from BPS Bioscience require a minimum order value above 400€Encompassing Amino Acids: 960-1367(end)
Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Description: Recombinant human IGF1 Receptor (insulin like growth factor 1 receptor) encompassing amino acids 960-1367 (end), containing the tyrosine kinase domain . This construct contains an N-terminal His-tag. The recombinant protein was affinity purified.
Format: Aqueous buffer solution
Formulation: 50 mM sodium phosphate, pH 7.0, 300 mM NaCl, 150 mM Imidazole, 0.1 mM PMSF, 0.25 mM DTT, 25% glycerol
Genbank: NM_000875
Purity: ≥80%
Storage Stability: At least 6 months at -80°C.
Tags: N-terminal His-tag
Uniprot: P08069
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: 1. Baer, K., et al., Biochemistry. 2001 Nov 27;40(47):14268-78.
2. Tennagels, N., et al., Biochem. Biophys. Res. Com. 1999 260: 724-8.Application Reference:
A highly selective dual insulin receptor (IR)/insulin-like growth factor 1 receptor (IGF-1R) inhibitor derived from an extracellular signal-regulated kinase (ERK) inhibitor (2014)
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