Application Note: IL-29 protein has been tested by SDS-PAGE and is suitable as a control for polyclonal or monoclonal anti-IL-29 in immunological assays.
Concentration Value: 0.1 mg/mL
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Other Performance Data: Biological Activity: Endotoxin Level: Measured by LAL is <0.01ng/µg or <0.1EU/µg.
Physical State: Lyophilized
Purity and Specificity: Purity was determined to be greater than 95% as determined by analysis by RP-HPLC by reducing and non-reducing SDS-PAGE against known standard.
Background: IL-29 (Interleukin-29) is a secreted cytokine with immunomodulatory activity. It may play a role in antiviral immunity. It up-regulates MHC class I antigen expression. IL-29 is a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway. Its induction is by viral infections or double stranded RNA. Recombinant IL-29 produced in E.coli is a single, non-glycosylated polypeptide chain containing 179 amino acids and having a molecular mass of 19,895 Daltons.
Low Endotoxin: Yes
Other: User Optimized