Application Note: WB: 0.125-0.5 μg/mL. ICC/IF: 5-20 μg/mL. IHC-P: 2-5 μg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 18
Form: Liquid
Buffer (with preservative): PBS, 0.02% Sodium azide.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq, Jul 2008]
Uniprot ID: Q16552
Antigen Species: Human
Immunogen: Peptide corresponding to 16 amino acids near the center of mature human IL-17. The immunogen is located within amino acids 50-100 of IL-17.
Purification: Purified by antigen-affinity chromatography
Conjugation: Unconjugated
Full Name: interleukin 17A
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