Abbreviation: IL4
Target Synonym: IL4;BCGF-1;BCGF1;BSF-1;BSF1;IL-4
Conjugation: Unconjugated
UNIProt ID: P05112
Background: The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Concentration: 1mg/mL
Immunogen: A synthetic peptide of human IL4
Dilution: WB 1:500-1:2000
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