iLite® IL-23, Assay Ready Cells

The iLite® IL-23 Assay Ready Cells can be used for the quantification of IL-23 or p40 inhibitor activity, or the neutralizing antibody response against such inhibitors in human serum. Interleukin 23 (IL-23) is a heterodimeric pro-inflammatory cytokine that shares traits with IL-12. Both cytokines contain the p40 subunit which binds to the receptor chain IL-12Rβ1. However, the two cytokines exert distinct non-redundant biological functions. IL-23 has been implicated as an inflammation mediator in several autoimmune diseases, and has also been found to promote tumour growth. Therapeutic agents targeting both IL-12 and IL-23 cytokines are currently used to treat psoriasis and psoriatic arthritis, and related agents are in clinical testing for a variety of inflammatory disorders.

• SKU: WIEBM4023
• Manufacturer: Svar Life Science / Eurodiagnostica
• Manufacturer SKU: BM4023
• Package Unit: 250 µL
• Quantity Unit: PAK