Clone Name: EP286
Application Note: IHC-P: 1:50-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 64
Positive Control: Pancreatic ductal adenocarcinoma
Form: Liquid
Buffer (with preservative): Tris-HCl buffer, 0.2% BSA, 0.09% Sodium azide.
Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)
Background: The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes. [provided by RefSeq, Jul 2008]
Uniprot ID: O00425
Antigen Species: Human
Immunogen: Recombinant fragment within Human IMP3 Cellular Localization: Cytoplasmic
Purification: Purified IgG
Conjugation: Unconjugated
Full Name: insulin like growth factor 2 mRNA binding protein 3
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