Inaxaplin, CAS 2446816-88-0

Formulation: A solid

Formal Name: 5,7-difluoro-2-(4-fluorophenyl)-N-[(3S,4R)-4-hydroxy-2-oxo-3-pyrrolidinyl]-1H-indole-3-propanamide

Purity: ≥98%

Formula Markup: C21H18F3N3O3

Formula Weight: 417,4

Shelf life (days): 1460

CAS Number: 2446816-88-0

Notes: Inaxaplin is an apolipoprotein L1 (ApoL1) inhibitor.{69966} It inhibits cytotoxicity induced by overexpression of the APOL1 variants G1 and G2 in cells when used at a concentration of 3 µM. Inaxaplin also reduces ApoL1 G1-induced inhibition of global protein synthesis in podocytes isolated from APOL1 transgenic mice. In vivo, inaxaplin (10 mg/kg) reduces podocyte injury and proteinuria in APOL1 transgenic mice.

• SKU: CAY40852-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 40852-5
• Package Unit: 5 mg
• Quantity Unit: STK