Application Note: WB: 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 115
Form: Liquid
Buffer (with preservative): PBS, 20% Glycerol, 0.025% ProClin 300.
Concentration: 1.43 mg/ml (Please refer to the vial label for the specific concentration.)
Background: The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
Uniprot ID: P13612
Antigen Species: Human
Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human Integrin alpha 4. The exact sequence is proprietary.
Purification: Purified by antigen-affinity chromatography.
Conjugation: Unconjugated
Full Name: integrin subunit alpha 4
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