Application Note: WB: 1:500-1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 20
Form: Liquid
Buffer (with preservative): PBS, pH 7.4, 150mM NaCl, 50% glycerol, 0.02% sodium azide.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]
Uniprot ID: Q13352
Antigen Species: Human
Immunogen: A synthesized peptide derived from human ITGB3BP(Accession Q13352), corresponding to amino acid residues S49-S71.
Purification: Purified by antigen-affinity chromatography
Conjugation: Unconjugated
Full Name: integrin subunit beta 3 binding protein
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