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Encompassing Amino Acids: 535-812
Description: Human Jak2 (JH2 pseudokinase domain), also known as Janus kinase-2, and Just Another Kinase 2, with E596A, V617F, W659A, W777A, and F794H mutations. GenBank Accession No. NM_004972, a.a. 535-812, with C-terminal His-Tag, MW=33 kDa, expressed in an Sf9 expression system.
Format: Aqueous buffer solution.
Formulation: 20 mM Tris pH 8.5, 0.5 mM TCEP and 10% glycerol
Genbank: NM_004972
Storage Stability: At least 6 months at -80°C.
Tags: C-terminal His-tag
Uniprot: O60674
Warnings: Avoid freeze/thaw cycles. Storing diluted enzyme is not recommended. If necessary, use carrier protein (BSA 0.1 - 0.5%).
Biosafety Level: Not applicable (BSL-1)
References: 1. Tono, C., et al., Leukemia. 2005; 19(10): 1843-1844.2. Goerttler, P.S., et al., Blood. 2005; 106(8): 2862-2864.
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