Product Type: Membrane Potential Probe
CAS No.: 3520-43-2
MolecularFormula: C25H27Cl4IN4
Molecular Weight: 652,2
Source: Synthetic
Purity: >98% (HPLC); NMR (Conforms)
Solubility: May be dissolved in DMSO (20 mg/ml)
Appearance: Red powder
PubChem CID: 5492929
Scientific Background: JC-1 is a fluorescent dye that is able to pass across the mitochondrial membrane. It is used to measure mitochondrial membrane potential. At low membrane potentials, it remains a monomer and emits green-fluorescent light (λex=485 nm, λem=520 nm). At higher membrane potentials, it forms "J-aggregates", which emit red-fluorescent light (λex=520-570 nm, λem=570-610 nm). The ratio of red/green fluorescence is based only on the membrane potential, and not on mitochondrial size, shape or density.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
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