K252B, CAS 99570-78-2

Kinase inhibitor

Product Type: Inhibitor

CAS No.: 99570-78-2

MolecularFormula: C26H19N3O5

Molecular Weight: 453,5

Source: Synthetic

Purity: ≥98% (HPLC)

Solubility: Soluble in DMSO (1 mg/ml) or dimethyl formamide (1 mg/ml)

Appearance: White solid

PubChem CID: 9981344

Scientific Background: K252B is a non-selective, protein kinase inhibitor. It inhibits CaMKII, MYLK, PKA, PKC, and cGKI. It acts by binding to the ATP binding domain of the kinase. K252B is cell permeable.

References: 1. Nakanishi S., Matsuda Y., Iwahashi K., & Kase H. (1986) J. Antibiotics 39(8): 1066–1071.2. Teshima R., et al. (1997) J. Immun. 159(2): 964–969.3. Knüsel B., et al. (1992) J. Neurochem. 59(2): 715–722.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• SKU: STRSIH-456-1MG
• Manufacturer: Stressmarq Biosciences
• Manufacturer SKU: SIH-456-1MG
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK