Clone: polyclonal.
Conjugate: APC.
Immunogen: Polyclonal immunoglobulin light chains of kappa type isolated from a pool of human sera for Rabbit Anti-Human Kappa Light Chains.
Storage Buffer: The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3).
Recommended Usage: Kappa, is a polyclonal antibody intended for simultaneous identification, detection/enumeration of kappa and lambda light chains. This reagent is effective for direct IF staining of human tissue for FCM analysis using ≤1 μg/106 cells.
Description: This antibody reacts with the Immunoglobulins bearing kappa light chains. The evaluation of cell surface Kappa/Lambda expression can identify clonally restricted B lymphocyte populations and thus can aide in the diagnosis of hematologic malignancy. Several B cell disorders are associated with decreased levels of Kappa/Lambda at the cell surface.
Immunoglobulins bearing kappa light chains are present on approximately 50% of normal B lymphocytes and on Ig + leukemic cells. In serum, Anti-Kappa reacts with immunoglobulins bearing kappa light chains as well as free kappa light chains.
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