Abbreviation: eIF4E
Target Synonym: AUTS19;CBP;EIF4E1;EIF4EL1;EIF4F;eIF-4E;EIF4E
Conjugation: Unconjugated
UNIProt ID: P06730
Background: The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants.
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human eIF4E
Dilution: WB 1:500-1:2000,IF 1:50-1:200,IHC 1:50-1:200
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