(KO Validated) CD33 Polyclonal Antibody, Rabbit

Abbreviation: CD33

Target Synonym: CD33; SIGLEC-3; SIGLEC3; p67; CD33 molecule

Conjugation: Unconjugated

UNIProt ID: P20138

Background: Myeloid cell surface antigen CD33 also known as Sialic acid binding Ig-like lectin 3, CD33 antigen or Siglec-3, is a member of the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. This Single-pass type I membrane protein contains 1 Ig-like C2-type (immunoglobulin-like) domain and 1 Ig-like V-type (immunoglobulin-like) domain. CD33/Siglec-3 induces apoptosis in acute myeloid leukemia (in vitro). CD33/Siglec-3 can function as a sialic acid-dependent cell adhesion molecule and that binding can be modulated by endogenous sialoglycoconjugates when CD33 is expressed in a plasma membrane.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human CD33

Dilution: WB 1:500-1:2000

• SKU: ELSE-AB-93328-60
• Manufacturer: Elabscience Biotechnology
• Manufacturer SKU: ELA-E-AB-93328-60
• Green Labware: No
• Package Unit: 60 µl
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Polyclonal
• Application: Western Blotting
• Isotype: IgG
• Host: Rabbit